Synergizing immunotherapy with embolization: Innovations and clinical strategies in liver tumour management
The combination of immunotherapy with embolization is rapidly reshaping the treatment landscape for primary and metastatic liver tumours, creating new opportunities to improve patient outcomes through synergistic approaches. As clinical evidence continues to grow, interventional oncologists must understand not only the technical aspects of intra-arterial therapies but also their immunological impact, optimal timing, and integration with systemic treatments.
This CIRSE webinar will explore the scientific rationale and clinical evidence behind combining embolization techniques such as cTACE, DEE-TACE, and TARE with immune-based systemic therapies. Experts will discuss patient selection, treatment sequencing, and the management of toxicities, while providing practical insights for daily clinical decision making. Attendees will also have the opportunity to interact with faculty during a live discussion and Q&A session.
Learning objectives
- Describe the mechanistic basis of combining immunotherapy with embolization in the management of primary and metastatic liver tumors.
- Summarize recent clinical evidence and outcomes pertaining to combination approaches in hepatocellular carcinoma (HCC) and colorectal liver metastases (CRLM).
- Recognize potential risks, immune-related toxicities, and strategies for multidisciplinary management in combination therapies.
- Discuss future directions, ongoing research, and evolving best practices in the field of interventional oncology and immuno-oncology.
Programme
Introduction by the moderators
Michal Mauda-Havakuk (Tel-Aviv/IL)
Evidence on trial: combining IAT and immunotherapy in palliation — what we know and what’s next
Paul Beunon (Villejuif/FR)
Precision in practice: choosing between cTACE vs. DEB-TACE in the immunotherapy era
Rony Avritscher (Houston/US)
Precision in practice: TARE in the immunotherapy era
TBC
ICI and combinations with IAT in a curative setting: downstaging and bridging to resection and transplantation
TBC
Discussion and Q&A
Take home points by moderators
Lynn Jeanette Savic (Berlin/DE)
Faculty
Moderators


Speakers
Rony Avritscher (Houston/US)
Paul Beunon (Villejuif/FR)
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